I set up two schedules on a couple websites that are close to launch.
Really, the backup files aren't too terribly big. So I set up one folder to do my daily backup, and I keep 7 of them.
Then, I set one to be hourly, since we're in crunch time, and multiple folks have their fingers in the system. If something goes wrong, I don't want to be unprepared.
It's not hard at all. 10 minutes to set up both, tops. Do it.
Hourly database backups. I keep 24.
Secondary daily backups. I keep 7.
This will be revisited when the heat comes off.